As a top-tier chiral pharmaceutical intermediate, D-p-Hydroxyphenylglycine (DHPG) is a high-demand material for international buyers sourcing key components for β-lactam antibiotics and fine chemicals. This concise guide covers core search hotspots—quality standards, HS code, supply chain insights, and market trends—to support your sourcing decisions.
What Is DHPG? Key Basics for Buyers
DHPG (CAS 22818-40-2) is a white crystalline powder with the molecular formula C₈H₉NO₃ (molecular weight 167.16) . The D-isomer (R-configured) is the most commercially critical, serving as an irreplaceable side-chain raw material for amoxicillin, cefoperazone, and cefradine—broad-spectrum antibiotics widely used in global healthcare . It also expands into high-end cosmetics and food additives due to its biocompatibility and safety.
Key specs for pharmaceutical use:
- Purity: ≥99.0% (HPLC/titration)
- Optical rotation: -155.0 to -160.0° (c=1, 1mol/L HCl)
- Storage: Cool, dark environment (<15°C) to preserve stability
Critical Sourcing and Compliance for Global Buyers
HS Code and Regulatory Compliance
- Global HS Code: 2922501000 (covers DHPG and its monopotassium salt) .
- Export/import requirements: Mandatory customs clearance documents (A/B permits) and hygiene inspection (R/S certificates) .
- Compliance standards: Align with FDA, EMA, ICH guidelines, and China’s HG/T 5804-2021 for pharmaceutical-grade quality.
How to Choose a Reliable DHPG Supplier?
- Verify certifications: Request CoA, SDS, and third-party test reports for purity, optical rotation, and impurity levels .
- Check production technology: Prioritize enzymatic or continuous-flow processes for sustainability and quality consistency.
- Confirm compliance: Ensure alignment with target market regulations and HS code requirements .
- Evaluate scalability: Assess capacity for bulk orders and customization (e.g., particle size, specific packaging).
Ready to Secure High-Quality DHPG for Your Business?
Don’t let sourcing challenges delay your pharmaceutical or fine chemical production—partner with a trusted supplier that delivers compliant, high-purity DHPG (CAS 22818-40-2) aligned with global standards (FDA/EMA/HG/T 5804-2021). Contact JULANCHEM today to request product samples, detailed CoA reports, or a customized quote for bulk orders. Act now to lock in competitive pricing and ensure stable supply—your next successful project starts with the right chiral intermediate partner!
Please contact us at 86-15251755320 or mail to info@julanchem.com
