High-Purity Chiral Intermediate for β-Lactam Antibiotics
Product Overview
D-p-Hydroxyphenylglycine (D-HPG) is a key chiral pharmaceutical intermediate widely used in the synthesis of semi-synthetic β-lactam antibiotics, including amoxicillin, cefadroxil, and cefalexin.
As an experienced manufacturer of API intermediates from China, we supply high-purity D-HPG with consistent quality, stable optical activity, and reliable batch-to-batch reproducibility — meeting the strict requirements of global pharmaceutical producers and procurement specialists.

Typical Applications
- Synthesis of Amoxicillin
- Synthesis of Cefadroxil
- Synthesis of Cefalexin
- Chiral building block for β-lactam antibiotics
- Pharmaceutical R&D and scale-up projects
Technical Specifications
| Item | Specification |
|---|---|
| Product Name | D-p-Hydroxyphenylglycine |
| Abbreviation | D-HPG |
| CAS No. | 22818-40-2 |
| Molecular Formula | C₈H₉NO₃ |
| Molecular Weight | 167.16 |
| Appearance | White to off-white crystalline powder |
| Optical Rotation | Conforms to D-configuration |
| Assay (HPLC) | ≥ 99.0% |
| Enantiomeric Purity | ≥ 99% ee |
| Loss on Drying | ≤ 0.5% |
| Packaging | 25 kg fiber drum or customized |
| Storage | Cool, dry, well-ventilated area |
Specifications can be adjusted according to pharmacopeial or customer-specific requirements.
Quality & Compliance
- Manufactured under strict quality management systems
- Full COA, MSDS, and technical documentation available
- Suitable for regulated pharmaceutical supply chains
- Experienced in exporting API intermediates to global markets
Why Choose Us
- Dedicated pharmaceutical intermediate production lines
- Strong process optimization and cost control
- Professional international procurement support
- Fast response for samples, quotations, and technical inquiries
We don’t just supply chemicals — we support your procurement efficiency and production success.
Contact Us
📩 Looking for a reliable D-HPG supplier in China?
Contact us today to request samples, technical data, or a competitive quotation.
👉 Send your inquiry now and let our technical team support your project from sourcing to scale-up.


