Reliable 5-Fluorouracil manufacturer supplying pharmaceutical grade 5-FU (CAS 51-21-8) for anticancer drug production. Support custom packaging, bulk orders & global regulatory compliance. Get instant quote now!
Product Overview: 5-Fluorouracil (5-FU)
5-Fluorouracil (CAS No.: 51-21-8), commonly known as 5-FU, is a key nucleoside antimetabolite API widely used in the synthesis of anticancer pharmaceuticals. As a professional 5-Fluorouracil manufacturer in China, we produce high-purity 5-FU through advanced chemical synthesis technology, ensuring consistent quality that meets USP, EP, and BP standards. Our 5-Fluorouracil is mainly applied in the production of drugs for treating colorectal cancer, breast cancer, gastric cancer, and pancreatic cancer, trusted by pharmaceutical companies and research institutions worldwide.
Technical Specifications
| Item | Specification | Test Method |
|---|---|---|
| Chemical Name | 5-Fluoro-2,4(1H,3H)-pyrimidine dione | – |
| CAS Number | 51-21-8 | – |
| Synonyms | 5-FU; NSC 19893; 5-Fluoro-uracil | – |
| Molecular Formula | C₄H₃FN₂O₂ | – |
| Molecular Weight | 130.08 | – |
| Appearance | White to off-white crystalline powder | Visual Inspection |
| Purity | ≥99.0% | HPLC |
| Melting Point | 282-286°C (decomposition) | USPAppendix |
| Solubility | Soluble in DMSO (13.01 mg/ml), slightly soluble in ethanol, soluble in water (30 mg/ml at 20°C) | USP Appendix |
| Loss on Drying | ≤0.5% | 105°C, 2hrs |
| Residue on Ignition | ≤0.1% | USP Appendix |
| Heavy Metals | ≤10 ppm | Atomic Absorption Spectroscopy |
| Storage Condition | Store at 2-8°C, protect from light and moisture; retain in carton until use | – |
| Shelf Life | 2 years when stored as recommended | – |
Applications
5-Fluorouracil is a critical API for the synthesis of anticancer drugs. Its main applications include:
- Production of intravenous injection drugs for treating colorectal cancer, breast cancer, gastric cancer, pancreatic cancer, and esophageal cancer
- Research and development of novel antimetabolite anticancer drugs
- Synthesis of pharmaceutical intermediates and reference standards
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