D-p-Hydroxyphenylglycine (D-HPG)

High-Purity Chiral Intermediate for β-Lactam Antibiotics

Product Overview

D-p-Hydroxyphenylglycine (D-HPG) is a key chiral pharmaceutical intermediate widely used in the synthesis of semi-synthetic β-lactam antibiotics, including amoxicillin, cefadroxil, and cefalexin.

As an experienced manufacturer of API intermediates from China, we supply high-purity D-HPG with consistent quality, stable optical activity, and reliable batch-to-batch reproducibility — meeting the strict requirements of global pharmaceutical producers and procurement specialists.

对羟基苯甘氨酸

Typical Applications

  • Synthesis of Amoxicillin
  • Synthesis of Cefadroxil
  • Synthesis of Cefalexin
  • Chiral building block for β-lactam antibiotics
  • Pharmaceutical R&D and scale-up projects

Technical Specifications

ItemSpecification
Product NameD-p-Hydroxyphenylglycine
AbbreviationD-HPG
CAS No.22818-40-2
Molecular FormulaC₈H₉NO₃
Molecular Weight167.16
AppearanceWhite to off-white crystalline powder
Optical RotationConforms to D-configuration
Assay (HPLC)≥ 99.0%
Enantiomeric Purity≥ 99% ee
Loss on Drying≤ 0.5%
Packaging25 kg fiber drum or customized
StorageCool, dry, well-ventilated area

Specifications can be adjusted according to pharmacopeial or customer-specific requirements.

Quality & Compliance

  • Manufactured under strict quality management systems
  • Full COA, MSDS, and technical documentation available
  • Suitable for regulated pharmaceutical supply chains
  • Experienced in exporting API intermediates to global markets

Why Choose Us

  • Dedicated pharmaceutical intermediate production lines
  • Strong process optimization and cost control
  • Professional international procurement support
  • Fast response for samples, quotations, and technical inquiries

We don’t just supply chemicals — we support your procurement efficiency and production success.

Contact Us

📩 Looking for a reliable D-HPG supplier in China?
Contact us today to request samples, technical data, or a competitive quotation.

👉 Send your inquiry now and let our technical team support your project from sourcing to scale-up.

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