As a leading 7-ACA manufacturer and supplier with GMP certification, we provide high-purity 7-Aminocephalosporanic acid (CAS No.: 957-68-6) tailored for global pharmaceutical enterprises. 7-ACA is the core intermediate for synthesizing third-generation, fourth-generation cephalosporin antibiotics, widely applied in producing cefotaxime, ceftriaxone, cefoperazone, and other clinical essential antibiotics. Our 7-ACA product meets international quality standards such as USP, EP, and BP, ensuring stable performance in antibiotic synthesis processes. With a professional R&D team and mature production lines, we guarantee reliable supply capacity and competitive pricing for bulk 7-ACA procurement worldwide.
Product Overview
7-Aminocephalosporanic acid (7-ACA) is a white to off-white crystalline powder derived from cephalosporin C through enzymatic hydrolysis. It possesses the basic cephem ring structure, which is the key active moiety for cephalosporin antibiotics. Our 7-ACA is produced via advanced enzymatic synthesis technology, featuring high purity, low impurity content, and excellent reactivity—effectively improving the yield and quality of downstream cephalosporin products. Whether you are looking for USP grade 7-ACA, EP grade 7-ACA, or customized specifications, we can meet your diverse procurement needs.
Technical Specifications
| Item | Specification (USP/EP/BP Standard) | Test Method |
|---|---|---|
| Appearance | White to off-white crystalline powder | Visual Inspection |
| Purity (HPLC) | ≥99.0% | HPLC |
| Single Impurity (HPLC) | ≤0.5% | HPLC |
| Total Impurities (HPLC) | ≤1.0% | HPLC |
| Specific Rotation ([α]₂₀/D) | +105° ~ +120° | Polarimetry |
| Loss on Drying | ≤1.0% | 105℃, 3h |
| Residue on Ignition | ≤0.2% | 800℃, 1h |
| Heavy Metals | ≤10 ppm | Atomic Absorption Spectrometry |
| Microbial Limit | Total Aerobic Microbial Count ≤100 CFU/g; Yeast & Mold ≤10 CFU/g; No Escherichia coli detected | Microbiological Test |
Application Fields
7-Aminocephalosporanic acid (7-ACA) is the most important intermediate in the cephalosporin antibiotic industry. It is mainly used for synthesizing a variety of cephalosporin antibiotics, including but not limited to:
- Third-generation cephalosporins: Ceftriaxone sodium, cefotaxime sodium, ceftazidime, cefoperazone sodium
- Fourth-generation cephalosporins: Cefepime, cefpirome
- Oral cephalosporins: Cefixime, cefpodoxime proxetil, cefdinir
Packaging & Storage
- Packaging: 10kg/20kg per fiber drum, lined with double-layer food-grade polyethylene bags; Customized packaging available for bulk orders.
- Storage: Store in a cool, dry, and well-ventilated warehouse, away from light and heat sources. Avoid contact with oxidants and strong acids/bases. Shelf life: 2 years under proper storage conditions.
Ready to Start Your Procurement? Contact Us Now!
For 7-ACA sample request, detailed COA, bulk pricing, or technical consultation, please contact today,we will respond to your inquiry within 24 hours.
Email: info@julanchem.com
WhatsApp/Phone: +86-15251755320
